Tag: coverage

30x means an average of 30 reads covering each base of your genome, which is enough for confident germline SNV and small-indel calling across roughly 90-95% of the reference. Here is the coverage math, the files you should insist on, and the QC steps we would run before trusting a single variant.

A gene panel is a subset of an exome, and an exome is about 1.5% of a genome. Here's how the three differ in coverage, cost, file sizes, and what you can re-analyze later.